As the poet-critic Gustave Kahn put it, Seurat was “a young man crazy about drawing.” He worked in conté crayon (a kind of greasy charcoal) on toothy Michallet paper, without the safety net of lines. Seurat just filled in tone, progressing from light, speckled grays to velvety blacks, until the drawing “developed” like a photographic print in the darkroom. Nominally, “Railway Tracks” is a precise view of a railroad embankment punctuated by electrical power poles and a tall stand of trees....

Oops. In a reversal of the usual sequence in science, researchers have discovered, after millions of people have received the drug, something fundamental about how Botox can act. Contrary to what turned up in preclinical testing, botulinum toxin can travel along neurons from the injection site into the brain, at least in lab animals. Researchers at Italy’s Institute of Neuroscience injected rats and mice with botulinum neurotoxin A in doses comparable to those used in people....

Just why top-selling Prozac and similar antidepressants work for PMS is unclear, says Dr. Meir Steiner of St. Joseph’s Hospital in Hamilton, Ontario, who led the study. What doctors do know is that raising levels of the brain chemical serotonin can alleviate tension and irritability. The study, published in last week’s New England Journal of Medicine, is the first to establish Prozac dosages for PMS. Nearly haft the women who took a high-end dosage of 60 mg dropped out, mainly because the side effects–insomnia, nausea–were so severe....

WATCH: Man Utd target Dembele’s double Southampton will curse their rotten luck having been the better side on the day and seeing a stick-on opening goal cancelled out by poor officiating but it was ultimately their inability to deal with Ibrahimovic which settled the EFL Cup final in United’s favour. United looked vulnerable from the start, with crosses from both wings flashing freely across the face of goal early on....

Later this year the concept may finally be emerging from the collective techie imagination. Danger Research, a 15-month-old company based in Palo Alto, Calif., will introduce a wireless gadget that it says will display the full variety of offerings on the Net–from graphical images on the Web to e-mail to instant messages. It’s meant to compete with RIM’s Blackberry pager, which sends and receives e-mail, and devices like the Palm VII, the Compaq iPaq or WAP phones, which download bits and pieces of customized Net content....

It was a melancholy flight: the leader of the free world, in the air and on the run, in his own country. The president flew to an Air Force base in Louisiana to refuel and to give Bush a chance to speak briefly to the people. The Secret Service advised him to fly deeper into the interior–a bitter reprise of his summer “Home to the Heartland” tour–to a command post in Nebraska....

Since World War II, American presidents have spoken to the country in time of crisis or uncertainty. The president is the only person elected by everyone, and his words have been looked to by Americans as a roadmap for hope to navigate future challenges. Thus far, President Trump has been dissuaded by his clueless political advisers from giving a nationwide address because, according to reporting, he has no new policy proposals to offer....

Unfortunately, that may have been the most energetic moment of the evening, save for co-moderator John Harris’s antic stage walks. For the most part, the contenders in the first GOP showdown of the nascent 2008 presidential campaign played it safe and stuck to their well-rehearsed scripts. They jockeyed for Reagan’s mantle—without engaging in much meaningful discussion of what parts of that legacy they liked, and what parts they didn’t. They slammed President Bush for his conduct of the Iraq War—but were careful not to otherwise distance themselves too much from the leader of their party....

Things used to be simpler. You worked for the same company nearly all your life and strived to do a decent honest job. The company, in turn, kept you employ provided training, gave annual raises, and if you performed well, advanced you up the corporate ladder. The notion of loyalty went beyond this alone. It spoke to a sense of family and an unspoken commitment to see one another through hard times....

Jones gets less respect from his former fellow pilots in the 93rd Tactical Fighter Squadron, a reserve unit flying out of Homestead Air Force Base. Maj. Alan Estis, a reservist who flies for an airline and who was slated to become the squadron’s next commander, told NEWSWEEK that he just resigned from the air force because he did not want to work for Jones. Most other pilots would not speak out publicly, but they gave NEWSWEEK copies of flight records and official memorandums clearly showing that senior officers in his squadron regarded Jones as an unsafe flier with an attitude problem....

America, but an opportunity. An incredible opportunity. While we should recognize that China and the United States are competitors, we should also understand that geopolitics and global economics are not zero-sum games. Just as a growing American economy is good for China, a growing Chinese economy is good for America. That means we have a stake in working together to solve common problems, rather than trying to browbeat or intimidate the other into action....

Of all athletes, then, Larry Joe Bird has been most at one with his sport consummate with basketball. His pedigree, the heritage, was just as exquisite. He came from Indiana–the Hoosier–where basketball has meant the most for the longest time, to go on to the Celtics, who have been the sovereignty of the sport for–eerily–exactly as long as he has lived. Bird came into this world in December 1956, the very week Bill Russell and K....

The second act was the rapid decline of Prime Minister Mori, a man not fit to be our leader in the first place. Even his fellow LDP members of Parliament say Mori was the last person they wanted to head the government. They call him by many unflattering names. Some say he is a man with a shark’s brain (meaning very small) and a flea’s heart (meaning no guts). Certainly, his mouth is too slippery to hold his tongue....

That Justice Kistler should be even faintly worried about his prospects is a reflection of this year’s new political reality: gay marriage is shaking up everything. As a federal amendment defining marriage as between a man and a woman only languishes in Congress–despite support from President George W. Bush–and Massachusetts prepares next week to start recognizing same-sex unions by court order, marriage battles are raging in volatile swing states like Oregon....

Yuri Sucart, once described by the government as a major distributor of steroids and human growth hormone in the criminal prosecution of Biogenesis, pleaded guilty in March in U.S. District Court in Miami to one count of conspiracy to distribute HGH, ESPN reported . MORE: Baseball’s worst everyday players | Each team’s worst MLB Draft misses On Thursday, U.S. District Judge Cecilia M. Altonaga also sentenced Sucart, 53, to serve six months of house arrest after his release from prison and fined him $5,000....

They have almost no history together, these three. With graduation beckoning – Lewis from Cleveland State and Lee from Drexel University – each player wondered if competing at a higher level with a clearer path to the NCAAs might be appealing. With Louisville losing 82 percent of the scoring from last season’s team, coach Rick Pitino desperately needed an infusion of talent and experience. So here they are now. They are, by definition, a team....